Non-Steroidal Anti-inflammatory drugs • Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the few groups of drugs available that actually treats the source of the pain (inflammation) as well as the pain itself.Because of this impact on the pathology that is causing the pain, NSAIDs should be considered any time that pain of inflammation is present o Most of the pain we treat involves some degree of inflammation (eg, surgery, trauma, osteoarthritis, cancer, etc...) • Advantages: Relatively long-lasting analgesia, easy to administer, anti-inflammatory, not controlled • Disadvantages: Not suitable for patients with some pre-existing diseases (eg, renal or hepatic disease, bleeding disorders).Alprazolam should be given cautiously to pets with liver or kidney disease, glaucoma, pregnant, are elderly, or in a debilitated condition.Taking alprazolam with antacids might slow the rate of absorption, and the two medications should be separated by at least two hours if being taken concurrently. If we want to do the best medicine possible and give our patients the best chance to heal, then we have to treat pain.Pain initiates a fairly profound stress response and a sympathetic overdrive.
Rambo does not like to be handled and loses his patience quickly. The cat pictured in this photo, Ollie, belongs to a staff member.Stress and autonomic imbalance are not benign and the cascade of side effects include gastrointestinal (GI) ileus, GI ulceration, clotting dysfunction, hypertension, tachycardia, tachyarrhythmias, and many others.Furthermore, stress and pain cause a fairly marked increase in cortisol release and a substantial increase in energy requirements, the latter of which may lead to a negative nitrogen balance and both of which impair healing.When he needs nail trims or vaccines, he is wrapped in a towel to protect our technicians, while he howls and struggles and tries to bite. He is a sweet and cuddly cat at home, but when he needed blood drawn and a sample of urine obtained, he became so stressed out and aggressive that he needed to be sedated with gas so we could handle him safely.The root cause of aggressive behavior in cats at the vet office is fear, and fearful cats are fractious cats.Fractious cats are a danger to themselves, as well as to our techs and doctors who have to examine and restrain them.